SCOPe 2.03: Domain d3my5c_: 3my5 C:

Lineage for d3my5c_ (3my5 C:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (335 PDB entries)
   Uniprot P24941

8. Domain d3my5c_: 3my5 C: [181691]
   Other proteins in same PDB: d3my5b1, d3my5b2, d3my5d1, d3my5d2
   automated match to d1ogua_
   complexed with fmt, rfz, sgm

Details for d3my5c_

PDB Entry: 3my5, 2.1 Å

PDB Description: CDk2/cyclinA in complex with DRB

PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d3my5c_:

Sequence, based on SEQRES records:

>d3my5c_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Sequence, based on observed residues (ATOM records):

>d3my5c_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgvvppldedgrsllsqmlhy
dpnkrisakaalahpffqdvtkpvphl

Timeline for d3my5c_:

• d3my5c_ first appeared in SCOPe 2.01
  
• d3my5c_ appears in SCOPe 2.02
  
• d3my5c_ appears in SCOPe 2.04
  
• d3my5c_ appears in the current release, SCOPe 2.08, called d3my5c1