SCOPe 2.01: Domain d3mxfa_: 3mxf A:

Lineage for d3mxfa_ (3mxf A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (2 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [189494] (1 PDB entry)

8. Domain d3mxfa_: 3mxf A: [181665]
   automated match to d1jm4b_
   complexed with dms, edo, iod, jq1

Details for d3mxfa_

PDB Entry: 3mxf, 1.6 Å

PDB Description: Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d3mxfa_:

Sequence; same for both SEQRES and ATOM records:

>d3mxfa_ a.29.2.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d3mxfa_:

• d3mxfa_ is new in SCOPe 2.01-stable
  
• d3mxfa_ appears in SCOPe 2.02
  
• d3mxfa_ appears in the current release, SCOPe 2.08