SCOPe 2.01: Domain d3mhwu_: 3mhw U:

Lineage for d3mhwu_ (3mhw U:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Urokinase-type plasminogen activator (LMW U-PA), catalytic domain [50586] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50587] (52 PDB entries)
   Uniprot P00749 156-178,179-424

8. Domain d3mhwu_: 3mhw U: [181232]
   automated match to d1ejna_
   complexed with abv, so4

Details for d3mhwu_

PDB Entry: 3mhw, 1.45 Å

PDB Description: the complex crystal structure of urokianse and 2-aminobenzothiazole

PDB Compounds: (U:) urokinase-type plasminogen activator

SCOPe Domain Sequences for d3mhwu_:

Sequence, based on SEQRES records:

>d3mhwu_ b.47.1.2 (U:) Urokinase-type plasminogen activator (LMW U-PA), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
slpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtke

Sequence, based on observed residues (ATOM records):

>d3mhwu_ b.47.1.2 (U:) Urokinase-type plasminogen activator (LMW U-PA), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadlahhndiallkirskegrcaqpsrtiqtis
lpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttkm
lcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpwi
rshtke

Timeline for d3mhwu_:

• d3mhwu_ is new in SCOPe 2.01-stable
  
• d3mhwu_ appears in SCOPe 2.02
  
• d3mhwu_ appears in the current release, SCOPe 2.08