SCOPe 2.03: Domain d3lo5e_: 3lo5 E:

Lineage for d3lo5e_ (3lo5 E:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (16 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (113 PDB entries)

8. Domain d3lo5e_: 3lo5 E: [180464]
   automated match to d121pa_
   complexed with ca, gdp, so4; mutant

Details for d3lo5e_

PDB Entry: 3lo5, 2.57 Å

PDB Description: crystal structure of the dominant negative s17n mutant of ras

PDB Compounds: (E:) gtpase hras

SCOPe Domain Sequences for d3lo5e_:

Sequence, based on SEQRES records:

>d3lo5e_ c.37.1.8 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgaggvgknaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

Sequence, based on observed residues (ATOM records):

>d3lo5e_ c.37.1.8 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgaggvgknaltiqliqnhfvdeydptiedsyrkqvvidgetclldilmrtg
egflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdlaartvesrqaqdlar
sygipyietsaktrqgvedafytlvreirqh

Timeline for d3lo5e_:

• d3lo5e_ first appeared in SCOPe 2.01
  
• d3lo5e_ appears in SCOPe 2.02
  
• d3lo5e_ appears in SCOPe 2.04
  
• d3lo5e_ appears in the current release, SCOPe 2.08