SCOPe 2.03: Domain d3l03b_: 3l03 B:

Lineage for d3l03b_ (3l03 B:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (121 PDB entries)

8. Domain d3l03b_: 3l03 B: [179834]
   automated match to d1qkua_
   protein/DNA complex; complexed with 4oh, cl, gol

Details for d3l03b_

PDB Entry: 3l03, 1.9 Å

PDB Description: crystal structure of human estrogen receptor alpha ligand-binding domain in complex with a glucocorticoid receptor interacting protein 1 nr box ii peptide and estetrol (estra-1,3,5(10)-triene-3,15 alpha, 16alpha,17beta-tetrol)

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d3l03b_:

Sequence, based on SEQRES records:

>d3l03b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllleml
dahrlh

Sequence, based on observed residues (ATOM records):

>d3l03b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsksleekdhihrvldkitdtli
hlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldah
rlh

Timeline for d3l03b_:

• d3l03b_ first appeared in SCOPe 2.01
  
• d3l03b_ appears in SCOPe 2.02
  
• d3l03b_ appears in SCOPe 2.04
  
• d3l03b_ appears in the current release, SCOPe 2.08