SCOPe 2.05: Domain d3ky2a_: 3ky2 A:

Lineage for d3ky2a_ (3ky2 A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (29 PDB entries)

8. Domain d3ky2a_: 3ky2 A: [179803]
   automated match to d1agwb_
   complexed with so4

Details for d3ky2a_

PDB Entry: 3ky2, 2.7 Å

PDB Description: crystal structure of fibroblast growth factor receptor 1 kinase domain

PDB Compounds: (A:) Basic fibroblast growth factor receptor 1

SCOPe Domain Sequences for d3ky2a_:

Sequence, based on SEQRES records:

>d3ky2a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
hmagvseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkm
lksdatekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqa
rrppgleysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtedn
vmkiadfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweift
lggspypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedld
rivaltsnq

Sequence, based on observed residues (ATOM records):

>d3ky2a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
hmagvseyelpedprwelprdrlvlgkplgeggqvvlaeaigldkdkpnrvtkvavkmlk
sdatekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarr
ppgleysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvm
kiadfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlg
gspypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldri
valtsnq

Timeline for d3ky2a_:

• d3ky2a_ first appeared in SCOPe 2.01
  
• d3ky2a_ appears in SCOPe 2.04
  
• d3ky2a_ is called d3ky2a1 in SCOPe 2.06
  
• d3ky2a_ appears in the current release, SCOPe 2.08, called d3ky2a1