SCOPe 2.01: Domain d3krla_: 3krl A:

Lineage for d3krla_ (3krl A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (254 PDB entries)

8. Domain d3krla_: 3krl A: [179622]
   automated match to d1t45a_
   complexed with krl, so4

Details for d3krla_

PDB Entry: 3krl, 2.4 Å

PDB Description: cfms tyrosine kinase in complex with 5-cyano-furan-2-carboxylic acid [4-(4-methyl-piperazin-1-yl)-2-piperidin-1-yl-phenyl]-amide

PDB Compounds: (A:) Macrophage colony-stimulating factor 1 receptor, Basic fibroblast growth factor receptor 1

SCOPe Domain Sequences for d3krla_:

Sequence, based on SEQRES records:

>d3krla_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kyqvrwkiiesyegnsytfidptqlpynekwefprnnlqfgktlgagafgkvveatafgl
gkedavlkvavkmlkstahadekealmselkimshlgqhenivnllgacthggpvlvite
yccygdllnflrrkrppgleysynpshnpeeqlssrdllhfssqvaqgmaflaskncihr
dvaarnvlltnghvakigdfglardimndsnyivkgnarlpvkwmapesifdcvytvqsd
vwsygillweifslglnpypgilvnskfyklvkdgyqmaqpafapkniysimqacwalep
thrptfqqicsflqe

Sequence, based on observed residues (ATOM records):

>d3krla_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kyqvrwkiipynekwefprnnlqfgktlgagafgkvveatafglgkedavlkvavkmlks
taadekealmselkimshlgqhenivnllgacthggpvlviteyccygdllnflrrkrql
ssrdllhfssqvaqgmaflaskncihrdvaarnvlltnghvakigdfglardimndsnyi
vkgarlpvkwmapesifdcvytvqsdvwsygillweifslglnpypgilvnskfyklvkd
gyqmaqpafapkniysimqacwalepthrptfqqicsflqe

Timeline for d3krla_:

• d3krla_ is new in SCOPe 2.01-stable
  
• d3krla_ appears in SCOPe 2.02
  
• d3krla_ appears in the current release, SCOPe 2.08