SCOPe 2.06: Domain d3krja_: 3krj A:

Lineage for d3krja_ (3krj A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d3krja_: 3krj A: [179621]
   automated match to d1t45a_
   complexed with act, krj

Details for d3krja_

PDB Entry: 3krj, 2.1 Å

PDB Description: cfms tyrosine kinase in complex with 4-cyano-1h-imidazole-2-carboxylic acid (2-cyclohex-1-enyl-4-piperidin-4-yl-phenyl)-amide

PDB Compounds: (A:) Macrophage colony-stimulating factor 1 receptor, Basic fibroblast growth factor receptor 1

SCOPe Domain Sequences for d3krja_:

Sequence, based on SEQRES records:

>d3krja_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pkyqvrwkiiesyegnsytfidptqlpynekwefprnnlqfgktlgagafgkvveatafg
lgkedavlkvavkmlkstahadekealmselkimshlgqhenivnllgacthggpvlvit
eyccygdllnflrrkrppgleysynpshnpeeqlssrdllhfssqvaqgmaflaskncih
rdvaarnvlltnghvakigdfglardimndsnyivkgnarlpvkwmapesifdcvytvqs
dvwsygillweifslglnpypgilvnskfyklvkdgyqmaqpafapkniysimqacwale
pthrptfqqicsflqeqa

Sequence, based on observed residues (ATOM records):

>d3krja_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pkyqvrwkiiesyegnsytfidptqlpynekwefprnnlqfgktlgagafgkvveatafg
lgkedavlkvavkmlkstahadekealmselkimshlgqhenivnllgacthggpvlvit
eyccygdllnflrrkrppgqlssrdllhfssqvaqgmaflaskncihrdvaarnvlltng
hvakigdfglardimndsnyivkgarlpvkwmapesifdcvytvqsdvwsygillweifs
lglnpypgilvnskfyklvkdgyqmaqpafapkniysimqacwalepthrptfqqicsfl
qeqa

Timeline for d3krja_:

• d3krja_ first appeared in SCOPe 2.01
  
• d3krja_ appears in SCOPe 2.05
  
• d3krja_ appears in SCOPe 2.07
  
• d3krja_ appears in the current release, SCOPe 2.08