SCOPe 2.03: Domain d3k8sa_: 3k8s A:

Lineage for d3k8sa_ (3k8s A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
7. Species Human (Homo sapiens) [TaxId:9606] [48525] (82 PDB entries)
   Uniprot P37231 232-505

8. Domain d3k8sa_: 3k8s A: [179198]
   automated match to d3prga_
   protein/DNA complex; complexed with z27

Details for d3k8sa_

PDB Entry: 3k8s, 2.55 Å

PDB Description: Crystal Structure of PPARg in complex with T2384

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3k8sa_:

Sequence, based on SEQRES records:

>d3k8sa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d3k8sa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytml
aslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiav
iilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehv
qllqvikktelhpllqeiykdl

Timeline for d3k8sa_:

• d3k8sa_ first appeared in SCOPe 2.01
  
• d3k8sa_ appears in SCOPe 2.02
  
• d3k8sa_ appears in SCOPe 2.04
  
• d3k8sa_ appears in the current release, SCOPe 2.08