SCOPe 2.01: Domain d3js2a_: 3js2 A:

Lineage for d3js2a_ (3js2 A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (8 PDB entries)

8. Domain d3js2a_: 3js2 A: [178748]
   automated match to d1agwb_
   complexed with po4, vm1

Details for d3js2a_

PDB Entry: 3js2, 2.2 Å

PDB Description: crystal structure of minimal kinase domain of fibroblast growth factor receptor 1 in complex with 5-(2-thienyl)nicotinic acid

PDB Compounds: (A:) Basic fibroblast growth factor receptor 1

SCOPe Domain Sequences for d3js2a_:

Sequence, based on SEQRES records:

>d3js2a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsn
qe

Sequence, based on observed residues (ATOM records):

>d3js2a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppglhn
peeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfglardihh
idyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelf
kllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

Timeline for d3js2a_:

• d3js2a_ is new in SCOPe 2.01-stable
  
• d3js2a_ appears in SCOPe 2.02
  
• d3js2a_ appears in the current release, SCOPe 2.08