SCOPe 2.08: Domain d3itna1: 3itn A:29-277

Lineage for d3itna1 (3itn A:29-277)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Apopain (caspase-3, cpp32) [52131] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52132] (28 PDB entries)

8. Domain d3itna1: 3itn A:29-277 [178614]
   Other proteins in same PDB: d3itna2
   automated match to d1nmqa_

Details for d3itna1

PDB Entry: 3itn, 1.63 Å

PDB Description: Crystal structure of Pseudo-activated Procaspase-3

PDB Compounds: (A:) Caspase-3

SCOPe Domain Sequences for d3itna1:

Sequence, based on SEQRES records:

>d3itna1 c.17.1.1 (A:29-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgietdsgvdddmachkipveadflyaystapgyyswrn
skdgswfiqslcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipciesm
ltkelyfyh

Sequence, based on observed residues (ATOM records):

>d3itna1 c.17.1.1 (A:29-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgiethkipveadflyaystapgyyswrnskdgswfiqs
lcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipciesmltkelyfyh

Timeline for d3itna1:

• d3itna1 first appeared in SCOPe 2.01, called d3itna_
  
• d3itna1 appears in SCOPe 2.07