SCOPe 2.05: Domain d3ic2a_: 3ic2 A:

Lineage for d3ic2a_ (3ic2 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.1: Globin-like [46457] (2 superfamilies)
   core: 6 helices; folded leaf, partly opened

4. Superfamily a.1.1: Globin-like [46458] (5 families)

5. Family a.1.1.2: Globins [46463] (27 proteins)
   Heme-binding protein

6. Protein Hemoglobin, alpha-chain [46486] (23 species)

7. Species Human (Homo sapiens) [TaxId:9606] [46487] (232 PDB entries)
   Uniprot P69905 P01922 P01934 P01935

8. Domain d3ic2a_: 3ic2 A: [178234]
   Other proteins in same PDB: d3ic2b_, d3ic2d_
   automated match to d1a00a_
   complexed with b78, hem, oxy, so4

Details for d3ic2a_

PDB Entry: 3ic2, 2.4 Å

PDB Description: crystal structure of liganded hemoglobin in complex with a potent antisickling agent, inn-266

PDB Compounds: (A:) Hemoglobin subunit alpha

SCOPe Domain Sequences for d3ic2a_:

Sequence; same for both SEQRES and ATOM records:

>d3ic2a_ a.1.1.2 (A:) Hemoglobin, alpha-chain {Human (Homo sapiens) [TaxId: 9606]}
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

Timeline for d3ic2a_:

• d3ic2a_ first appeared in SCOPe 2.01
  
• d3ic2a_ appears in SCOPe 2.04
  
• d3ic2a_ appears in SCOPe 2.06
  
• d3ic2a_ appears in the current release, SCOPe 2.08