SCOPe 2.06: Domain d3hm1b_: 3hm1 B:

Lineage for d3hm1b_ (3hm1 B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)

8. Domain d3hm1b_: 3hm1 B: [177687]
   automated match to d1qkua_
   protein/DNA complex; complexed with j3z

Details for d3hm1b_

PDB Entry: 3hm1, 2.33 Å

PDB Description: crystal structure of human estrogen receptor alpha ligand-binding domain in complex with a glucocorticoid receptor interacting protein 1 nr box ii peptide and estrone ((8r,9s,13s,14s)-3-hydroxy-13-methyl- 7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-one)

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d3hm1b_:

Sequence, based on SEQRES records:

>d3hm1b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
knslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwak
rvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmv
eifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldki
tdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllle
mldahrlh

Sequence, based on observed residues (ATOM records):

>d3hm1b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
knslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwak
rvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmv
eifdmllatssrfrmmnlqgeefvclksiillnsgvytflkdhihrvldkitdtlihlma
kagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahrlh

Timeline for d3hm1b_:

• d3hm1b_ first appeared in SCOPe 2.01
  
• d3hm1b_ appears in SCOPe 2.05
  
• d3hm1b_ appears in SCOPe 2.07
  
• d3hm1b_ appears in the current release, SCOPe 2.08