SCOP 1.63: Domain d1agsa1: 1ags A:80-221

Lineage for d1agsa1 (1ags A:80-221)

1. Root: SCOP 1.63

2. Class a: All alpha proteins [46456] (171 folds)

3. Fold a.45: Glutathione S-transferase (GST), C-terminal domain [47615] (1 superfamily)
   core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix

4. Superfamily a.45.1: Glutathione S-transferase (GST), C-terminal domain [47616] (1 family)
   this domains follows the thioredoxin-like N-terminal domain

5. Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain [47617] (15 proteins)

6. Protein Class alpha GST [81349] (6 species)

7. Species Human (Homo sapiens), (a1-1) [TaxId:9606] [47625] (10 PDB entries)

8. Domain d1agsa1: 1ags A:80-221 [17691]
   Other proteins in same PDB: d1agsa2, d1agsb2

Details for d1agsa1

PDB Entry: 1ags, 2.5 Å

PDB Description: a surface mutant (g82r) of a human alpha-glutathione s-transferase shows decreased thermal stability and a new mode of molecular association in the crystal

SCOP Domain Sequences for d1agsa1:

Sequence; same for both SEQRES and ATOM records:

>d1agsa1 a.45.1.1 (A:80-221) Class alpha GST {Human (Homo sapiens), (a1-1)}
lyrkdikekalidmyiegiadlgemilllpftqpeeqdaklalikekiknryfpafekvl
kshgqdylvgnklsradihlvellyyveeldsslissfpllkalktrisnlptvkkflqp
gsprkppmdeksleearkifrf

Timeline for d1agsa1:

• d1agsa1 first appeared (with stable ids) in SCOP 1.55
  
• d1agsa1 appears in SCOP 1.61
  
• d1agsa1 appears in SCOP 1.65
  
• d1agsa1 appears in the current release, SCOPe 2.08