SCOPe 2.08: Domain d3gp0a1: 3gp0 A:5-348

Lineage for d3gp0a1 (3gp0 A:5-348)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d3gp0a1: 3gp0 A:5-348 [176795]
   Other proteins in same PDB: d3gp0a2
   automated match to d1bmka_
   complexed with cl, edo, nil

Details for d3gp0a1

PDB Entry: 3gp0, 1.9 Å

PDB Description: Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib

PDB Compounds: (A:) Mitogen-activated protein kinase 11

SCOPe Domain Sequences for d3gp0a1:

Sequence, based on SEQRES records:

>d3gp0a1 d.144.1.7 (A:5-348) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ragfyrqelnktvwevpqrlqglrpvgsgaygsvcsaydarlrqkvavkklsrpfqslih
arrtyrelrllkhlkhenviglldvftpatsiedfsevylvttlmgadlnnivkcqalsd
ehvqflvyqllrglkyihsagiihrdlkpsnvavnedcelrildfglarqadeemtgyva
trwyrapeimlnwmhynqtvdiwsvgcimaellqgkalfpgsdyidqlkrimevvgtpsp
evlakissehartyiqslppmpqkdlssifrganplaidllgrmlvldsdqrvsaaeala
hayfsqyhdpedepeaepydesveakertleewkeltyqevlsf

Sequence, based on observed residues (ATOM records):

>d3gp0a1 d.144.1.7 (A:5-348) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ragfyrqelnktvwevpqrlqglrpvgsvcsaydarlrqkvavkklsrpfqsliharrty
relrllkhlkhenviglldvftpatsiedfsevylvttlmgadlnnivkcqalsdehvqf
lvyqllrglkyihsagiihrdlkpsnvavnedcelrildfgeemgyvatrwyrapeimln
wmhynqtvdiwsvgcimaellqgkalfpgsdyidqlkrimevvgtpspevlakissehar
tyiqslppmpqkdlssifrganplaidllgrmlvldsdqrvsaaealahayfsqyhdped
epeaepydesveakertleewkeltyqevlsf

Timeline for d3gp0a1:

• d3gp0a1 first appeared in SCOPe 2.01, called d3gp0a_
  
• d3gp0a1 appears in SCOPe 2.07