Lineage for d3fx5b_ (3fx5 B:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 955287Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 955288Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 955289Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 955305Protein Human immunodeficiency virus type 1 protease [50632] (5 species)
  7. 955367Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (378 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 955373Domain d3fx5b_: 3fx5 B: [176124]
    automated match to d1fgcc_
    complexed with gol, kni

Details for d3fx5b_

PDB Entry: 3fx5 (more details), 0.93 Å

PDB Description: Structure of HIV-1 Protease in Complex with Potent Inhibitor KNI-272 Determined by High Resolution X-ray Crystallography
PDB Compounds: (B:) Protease

SCOPe Domain Sequences for d3fx5b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3fx5b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}

SCOPe Domain Coordinates for d3fx5b_:

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Timeline for d3fx5b_: