Lineage for d3fv8a_ (3fv8 A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2979887Protein c-jun N-terminal kinase (jnk3s) [56137] (1 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 2979888Species Human (Homo sapiens) [TaxId:9606] [56138] (50 PDB entries)
  8. 2979930Domain d3fv8a_: 3fv8 A: [176075]
    automated match to d1jnka_
    complexed with edo, jk3

Details for d3fv8a_

PDB Entry: 3fv8 (more details), 2.28 Å

PDB Description: jnk3 bound to piperazine amide inhibitor, sr2774.
PDB Compounds: (A:) Mitogen-activated protein kinase 10

SCOPe Domain Sequences for d3fv8a_:

Sequence, based on SEQRES records: (download)

>d3fv8a_ d.144.1.7 (A:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyvv
tryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpe
fmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpa
krisvddalqhpyinvwydpaxxxxxderehtieewkeliykevmn

Sequence, based on observed residues (ATOM records): (download)

>d3fv8a_ d.144.1.7 (A:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglarvtryyrapevilg
mgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrny
venrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhp
yinvwydpaxxxxxderehtieewkeliykevmn

SCOPe Domain Coordinates for d3fv8a_:

Click to download the PDB-style file with coordinates for d3fv8a_.
(The format of our PDB-style files is described here.)

Timeline for d3fv8a_: