SCOPe 2.04: Domain d3ffgl_: 3ffg L:

Lineage for d3ffgl_ (3ffg L:)

1. Root: SCOPe 2.04

2. Class g: Small proteins [56992] (91 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein automated matches [190092] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187310] (66 PDB entries)

8. Domain d3ffgl_: 3ffg L: [175753]
   Other proteins in same PDB: d3ffga_
   automated match to d1g2lb_
   complexed with ffg

Details for d3ffgl_

PDB Entry: 3ffg, 1.54 Å

PDB Description: factor xa in complex with the inhibitor (r)-6-(2'-((3- hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin- 7(4h)-one

PDB Compounds: (L:) coagulation factor x, light chain

SCOPe Domain Sequences for d3ffgl_:

Sequence; same for both SEQRES and ATOM records:

>d3ffgl_ g.3.11.1 (L:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle

Timeline for d3ffgl_:

• d3ffgl_ first appeared in SCOPe 2.01
  
• d3ffgl_ appears in SCOPe 2.03
  
• d3ffgl_ appears in SCOPe 2.05
  
• d3ffgl_ appears in the current release, SCOPe 2.08