SCOPe 2.07: Domain d3eoaj_: 3eoa J:

Lineage for d3eoaj_ (3eoa J:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.62: vWA-like [53299] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.62.1: vWA-like [53300] (6 families)

5. Family c.62.1.1: Integrin A (or I) domain [53301] (12 proteins)

6. Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) [53302] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53303] (26 PDB entries)
   Uniprot P20701 153-334

8. Domain d3eoaj_: 3eoa J: [175115]
   Other proteins in same PDB: d3eoaa1, d3eoaa2, d3eoal1, d3eoal2
   automated match to d1lfaa_

Details for d3eoaj_

PDB Entry: 3eoa, 2.8 Å

PDB Description: Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I

PDB Compounds: (J:) Integrin alpha-L

SCOPe Domain Sequences for d3eoaj_:

Sequence; same for both SEQRES and ATOM records:

>d3eoaj_ c.62.1.1 (J:) Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) {Human (Homo sapiens) [TaxId: 9606]}
gnvdlvflfdgsmslqpdefqkildfmkdvmkklsntsyqfaavqfstsyktefdfsdyv
krkdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatdsgn
idaakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlftelqkki

Timeline for d3eoaj_:

• d3eoaj_ first appeared in SCOPe 2.01
  
• d3eoaj_ appears in SCOPe 2.06
  
• d3eoaj_ appears in the current release, SCOPe 2.08