SCOPe 2.06: Domain d3dmsa_: 3dms A:

Lineage for d3dmsa_ (3dms A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
   the active site is between the two identical subunits

6. Protein automated matches [190072] (19 species)
   not a true protein

7. Species Burkholderia pseudomallei [TaxId:28450] [188497] (1 PDB entry)

8. Domain d3dmsa_: 3dms A: [174063]
   automated match to d1ai2a_

Details for d3dmsa_

PDB Entry: 3dms, 1.65 Å

PDB Description: 1.65a crystal structure of isocitrate dehydrogenase from burkholderia pseudomallei

PDB Compounds: (A:) Isocitrate dehydrogenase [NADP]

SCOPe Domain Sequences for d3dmsa_:

Sequence, based on SEQRES records:

>d3dmsa_ c.77.1.1 (A:) automated matches {Burkholderia pseudomallei [TaxId: 28450]}
yqhikvpeggdkitvnkdfslnvsdqpiipyiegdgtgfditpvmikvvdaavekayggk
kkihwmeiyagekatkvygpdvwlpeetlqvlkeyvvsikgplttpvgggirslnvalrq
eldlyvclrpiqyfkgvpspvrepektnmvifrensediyagiewaaeseqakkvikflq
eemgvkkirfpqtsgigikpvskegterlvrkaiqyaidndrksvtlvhkgnimkftega
frdagyalaqkefgaelidggpwmkfknpktgneivvkdsiadaflqqillrpaeydvia
tlnlngdyisdalaaqvggigiapganlsdsvamfeathgtapkyagkdyvnpgseilsa
emmlrhlgwteaadviisameksikqkrvtydfarlmegatqvscsgfgqvlienme

Sequence, based on observed residues (ATOM records):

>d3dmsa_ c.77.1.1 (A:) automated matches {Burkholderia pseudomallei [TaxId: 28450]}
yqhikvpeggdkitvnkdfslnvsdqpiipyiegdgtgfditpvmikvvdaavekayggk
kkihwmeiyagekatkvygpdvwlpeetlqvlkeyvvsikgplttpvrslnvalrqeldl
yvclrpiqyfkgvpspvrepektnmvifrensediyagiewaaeseqakkvikflqeemg
vkkirfpqtsgigikpvskegterlvrkaiqyaidndrksvtlvhkgnimkftegafrda
gyalaqkefgaelidggpwmkfknpktgneivvkdsiadaflqqillrpaeydviatlnl
ngdyisdalaaqvggigiapganlsdsvamfeathgtapkyagkdyvnpgseilsaemml
rhlgwteaadviisameksikqkrvtydfarlmegatqvscsgfgqvlienme

Timeline for d3dmsa_:

• d3dmsa_ first appeared in SCOPe 2.01
  
• d3dmsa_ appears in SCOPe 2.05
  
• d3dmsa_ appears in SCOPe 2.07
  
• d3dmsa_ appears in the current release, SCOPe 2.08