SCOPe 2.03: Domain d3dkca_: 3dkc A:

Lineage for d3dkca_ (3dkc A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Hepatocyte growth factor receptor, c-MET [103300] (1 species)
   PTK group; HGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [103301] (34 PDB entries)

8. Domain d3dkca_: 3dkc A: [174029]
   automated match to d1r0pa_
   complexed with atp, cl, mg

Details for d3dkca_

PDB Entry: 3dkc, 1.52 Å

PDB Description: structure of met receptor tyrosine kinase in complex with atp

PDB Compounds: (A:) Met proto-oncogene

SCOPe Domain Sequences for d3dkca_:

Sequence; same for both SEQRES and ATOM records:

>d3dkca_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
vhidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavk
slnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfir
nethnptvkdligfglqvakgmkflaskkfvhrdlaarncmldekftvkvadfglardmy
dkefdsvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntf
ditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehyv
hvnatyvnvkeg

Timeline for d3dkca_:

• d3dkca_ first appeared in SCOPe 2.01
  
• d3dkca_ appears in SCOPe 2.02
  
• d3dkca_ appears in SCOPe 2.04
  
• d3dkca_ appears in the current release, SCOPe 2.08, called d3dkca1