SCOPe 2.03: Domain d3d6db_: 3d6d B:

Lineage for d3d6db_ (3d6d B:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
7. Species Human (Homo sapiens) [TaxId:9606] [48525] (82 PDB entries)
   Uniprot P37231 232-505

8. Domain d3d6db_: 3d6d B: [173714]
   automated match to d1nyxa_
   protein/DNA complex; complexed with lrg

Details for d3d6db_

PDB Entry: 3d6d, 2.4 Å

PDB Description: Crystal Structure of the complex between PPARgamma LBD and the LT175(R-enantiomer)

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3d6db_:

Sequence; same for both SEQRES and ATOM records:

>d3d6db_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdl

Timeline for d3d6db_:

• d3d6db_ first appeared in SCOPe 2.01
  
• d3d6db_ appears in SCOPe 2.02
  
• d3d6db_ appears in SCOPe 2.04
  
• d3d6db_ appears in the current release, SCOPe 2.08