SCOPe 2.08: Domain d3d23d_: 3d23 D:

Lineage for d3d23d_ (3d23 D:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (8 species)
   contains an extra alpha-helical domain

7. Species Human coronavirus [TaxId:443239] [188597] (6 PDB entries)

8. Domain d3d23d_: 3d23 D: [173630]
   Other proteins in same PDB: d3d23a2, d3d23b2
   automated match to d1uj1b_
   protein/RNA complex
   has additional subdomain(s) that are not in the common domain

Details for d3d23d_

PDB Entry: 3d23, 2.5 Å

PDB Description: main protease of hcov-hku1

PDB Compounds: (D:) 3C-like proteinase

SCOPe Domain Sequences for d3d23d_:

Sequence; same for both SEQRES and ATOM records:

>d3d23d_ b.47.1.4 (D:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {Human coronavirus [TaxId: 443239]}
sgivkmvsptskiepcivsvtygsmtlnglwlddkvycprhvicsssnmnepdysallcr
vtlgdftimsgrmsltvvsyqmqgcqlvltvslqnpytpkytfgnvkpgetftvlaayng
rpqgafhvtmrssytikgsflcgscgsvgyvltgdsvkfvymhqlelstgchtgtdftgn
fygpyrdaqvvqlpvkdyvqtvnviawlyaailnncawfvqndvcstedfnvwamangfs
qvkadlvldalasmtgvsietllaaikrlymgfqgrqilgsctfedelapsdvyqqlag

Timeline for d3d23d_:

• d3d23d_ first appeared in SCOPe 2.01
  
• d3d23d_ appears in SCOPe 2.07