SCOPe 2.06: Domain d1ctra_: 1ctr A:

Lineage for d1ctra_ (1ctr A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
   Duplication: made with two pairs of EF-hands

6. Protein Calmodulin [47516] (12 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47517] (88 PDB entries)
   Uniprot P02593

8. Domain d1ctra_: 1ctr A: [17264]
   trifluoperazine 1:1 complex
   complexed with ca, tfp

Details for d1ctra_

PDB Entry: 1ctr, 2.45 Å

PDB Description: drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex

PDB Compounds: (A:) calmodulin

SCOPe Domain Sequences for d1ctra_:

Sequence, based on SEQRES records:

>d1ctra_ a.39.1.5 (A:) Calmodulin {Human (Homo sapiens) [TaxId: 9606]}
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
vdemireadidgdgqvnyeefvqmmta

Sequence, based on observed residues (ATOM records):

>d1ctra_ a.39.1.5 (A:) Calmodulin {Human (Homo sapiens) [TaxId: 9606]}
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdemi
readidgdgqvnyeefvqmmta

Timeline for d1ctra_:

• d1ctra_ first appeared (with stable ids) in SCOP 1.55, called d1ctr__
  
• d1ctra_ appears in SCOPe 2.05
  
• d1ctra_ appears in SCOPe 2.07
  
• d1ctra_ appears in the current release, SCOPe 2.08