SCOPe 2.02: Domain d3adsb_: 3ads B:

Lineage for d3adsb_ (3ads B:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (102 PDB entries)

8. Domain d3adsb_: 3ads B: [172014]
   automated match to d1nyxa_
   protein/DNA complex; complexed with imn

Details for d3adsb_

PDB Entry: 3ads, 2.25 Å

PDB Description: Human PPARgamma ligand-binding domain in complex with indomethacin

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3adsb_:

Sequence, based on SEQRES records:

>d3adsb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiy

Sequence, based on observed residues (ATOM records):

>d3adsb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkkspfviydmnslmmgedkikfkkeva
irifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdg
vlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrp
gllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikk
tethpllqeiy

Timeline for d3adsb_:

• d3adsb_ first appeared in SCOPe 2.01
  
• d3adsb_ appears in SCOPe 2.03
  
• d3adsb_ appears in the current release, SCOPe 2.08