SCOPe 2.03: Domain d3a8ca_: 3a8c A:

Lineage for d3a8ca_ (3a8c A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Trypsin(ogen) [50515] (9 species)

7. Species Cow (Bos taurus) [TaxId:9913] [50516] (392 PDB entries)
   Uniprot P00760

8. Domain d3a8ca_: 3a8c A: [171865]
   automated match to d1aq7a_
   complexed with ca, o09

Details for d3a8ca_

PDB Entry: 3a8c, 1.85 Å

PDB Description: Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking with mixture of [(E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid] and [(E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid])

PDB Compounds: (A:) cationic trypsin

SCOPe Domain Sequences for d3a8ca_:

Sequence; same for both SEQRES and ATOM records:

>d3a8ca_ b.47.1.2 (A:) Trypsin(ogen) {Cow (Bos taurus) [TaxId: 9913]}
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscqgdsggp
vvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn

Timeline for d3a8ca_:

• d3a8ca_ first appeared in SCOPe 2.01
  
• d3a8ca_ appears in SCOPe 2.02
  
• d3a8ca_ appears in SCOPe 2.04
  
• d3a8ca_ appears in the current release, SCOPe 2.08