Lineage for d2ztwa_ (2ztw A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2905791Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2905792Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 2905793Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
    the active site is between the two identical subunits
  6. 2905990Protein automated matches [190072] (22 species)
    not a true protein
  7. 2906126Species Thermus thermophilus [TaxId:274] [189081] (6 PDB entries)
  8. 2906134Domain d2ztwa_: 2ztw A: [171518]
    automated match to d1g2ua_
    complexed with dei, mg, nad

Details for d2ztwa_

PDB Entry: 2ztw (more details), 2.79 Å

PDB Description: Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+
PDB Compounds: (A:) 3-isopropylmalate dehydrogenase

SCOPe Domain Sequences for d2ztwa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ztwa_ c.77.1.1 (A:) automated matches {Thermus thermophilus [TaxId: 274]}
mkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrkg
veeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplke
eiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrrkhv
vsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnifg
dilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammleh
afglvelarkvedavakalletpppdlggsagteaftatvlrhla

SCOPe Domain Coordinates for d2ztwa_:

Click to download the PDB-style file with coordinates for d2ztwa_.
(The format of our PDB-style files is described here.)

Timeline for d2ztwa_: