SCOPe 2.02: Domain d2zk5b_: 2zk5 B:

Lineage for d2zk5b_ (2zk5 B:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (76 PDB entries)
   Uniprot P37231 232-505

8. Domain d2zk5b_: 2zk5 B: [171276]
   automated match to d1nyxa_
   protein/DNA complex; complexed with nro

Details for d2zk5b_

PDB Entry: 2zk5, 2.45 Å

PDB Description: Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with nitro-233

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d2zk5b_:

Sequence, based on SEQRES records:

>d2zk5b_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiy

Sequence, based on observed residues (ATOM records):

>d2zk5b_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktethpllqeiy

Timeline for d2zk5b_:

• d2zk5b_ first appeared in SCOPe 2.01
  
• d2zk5b_ appears in SCOPe 2.03
  
• d2zk5b_ appears in the current release, SCOPe 2.08