SCOPe 2.02: Domain d2xnna_: 2xnn A:

Lineage for d2xnna_ (2xnn A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)

8. Domain d2xnna_: 2xnn A: [170254]
   automated match to d2java1
   complexed with 430, cl, edo

Details for d2xnna_

PDB Entry: 2xnn, 2.5 Å

PDB Description: structure of nek2 bound to cct242430

PDB Compounds: (A:) serine/threonine-protein kinase nek2

SCOPe Domain Sequences for d2xnna_:

Sequence, based on SEQRES records:

>d2xnna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllrel
khpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtqltl
alkechrrsdgghtvlhrdlkpanvfldgkqnvklgdfglarilnhdtsfaktfvgtpyy
mspeqmnrmsyneksdiwslgcllyelcalmppftafsqkelagkiregkfrripyrysd
elneiitrmlnlkdyhrpsveeilenplilehhhhhh

Sequence, based on observed residues (ATOM records):

>d2xnna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sraedyevlytigtygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllrelkh
pnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtqltlal
kechrrsrdlkpanvfldgkqnvklgdfgfvgtpyymspeqmnryneksdiwslgcllye
lcalmppftafsqkelagkiregkfrripyrysdelneiitrmlnlkdyhrpsveeilen
plilehhhhhh

Timeline for d2xnna_:

• d2xnna_ first appeared in SCOPe 2.01
  
• d2xnna_ appears in SCOPe 2.03
  
• d2xnna_ appears in the current release, SCOPe 2.08, called d2xnna1