SCOPe 2.05: Domain d2x0sa3: 2x0s A:1-405

Lineage for d2x0sa3 (2x0s A:1-405)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.1: Glutathione synthetase ATP-binding domain-like [56059] (10 families)

5. Family d.142.1.5: Pyruvate phosphate dikinase, N-terminal domain [56085] (1 protein)
   automatically mapped to Pfam PF01326

6. Protein Pyruvate phosphate dikinase, N-terminal domain [56086] (3 species)
   the common fold is interrupted by a 4-helical subdomain (residues 112-198)

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [75557] (1 PDB entry)

8. Domain d2x0sa3: 2x0s A:1-405 [169776]
   Other proteins in same PDB: d2x0sa1, d2x0sa2

Details for d2x0sa3

PDB Entry: 2x0s, 3 Å

PDB Description: 3.0 a resolution crystal structure of glycosomal pyruvate phosphate dikinase from trypanosoma brucei

PDB Compounds: (A:) pyruvate phosphate dikinase

SCOPe Domain Sequences for d2x0sa3:

Sequence, based on SEQRES records:

>d2x0sa3 d.142.1.5 (A:1-405) Pyruvate phosphate dikinase, N-terminal domain {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
vakkwvyyfgggnadgnknmkellggkganlaemvnlgipvppgftitteacktyqetet
ipqevadqvrenvsrvekemgakfgdpanpllfsvrsgaaasmpgmmdtvlnlglnkvtv
dawvrraprlerfvydsyrrfitmyadivmqvgredfeealsrmkerrgtkfdtdltasd
lkelcdgylelfelktgcsfpqdpvmqlfaaikavfrswgnpratiyrrmnnitgllgta
vnvqamvfgnindrsatgvafsrspstgenfffgeylvnaqgedvvagirtpqqinhsls
lrwakahgvgeeerrkrypsmeeampenyrllcdvrkrlenhyrdmqdleftvqdgrlwl
lqcrngkrtihaavriaidmvneglisreeavlridpyqvdhlmh

Sequence, based on observed residues (ATOM records):

>d2x0sa3 d.142.1.5 (A:1-405) Pyruvate phosphate dikinase, N-terminal domain {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
vakkwvyyfgggnadgnknmkellggkganlaemvnlgipvppgftitteacktyqetet
ipqevadqvrenvsrvekemgakfgdpanpllfsvrsgaaasmdtvlnlglnkvtvdawv
rraprlerfvydsyrrfitmyadivmqvgredfeealsrmkerrgtkfdtdltasdlkel
cdgylelfelktgcsfpqdpvmqlfaaikavfrswgnpratiyrrmnnitgllgtavnvq
amvfgnindrsatgvafsrspstgenfffgeylvnaqgedvvagirtpqqinhslslrwa
kahgvgeeerrkrypsmeeampenyrllcdvrkrlenhyrdmqdleftvqdgrlwllqcr
ngkrtihaavriaidmvneglisreeavlridpyqvdhlmh

Timeline for d2x0sa3:

• d2x0sa3 first appeared in SCOPe 2.01
  
• d2x0sa3 appears in SCOPe 2.04
  
• d2x0sa3 appears in SCOPe 2.06
  
• d2x0sa3 appears in the current release, SCOPe 2.08