SCOPe 2.03: Domain d2wxvc_: 2wxv C:

Lineage for d2wxvc_ (2wxv C:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d2wxvc_: 2wxv C: [169685]
   Other proteins in same PDB: d2wxvb1, d2wxvb2, d2wxvd1, d2wxvd2
   automated match to d1vywa_
   complexed with so4, wxv

Details for d2wxvc_

PDB Entry: 2wxv, 2.6 Å

PDB Description: structure of cdk2-cyclin a with a pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor

PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d2wxvc_:

Sequence; same for both SEQRES and ATOM records:

>d2wxvc_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d2wxvc_:

• d2wxvc_ first appeared in SCOPe 2.01
  
• d2wxvc_ appears in SCOPe 2.02
  
• d2wxvc_ appears in SCOPe 2.04
  
• d2wxvc_ appears in the current release, SCOPe 2.08, called d2wxvc1