SCOPe 2.06: Domain d2wmba1: 2wmb A:1-296

Lineage for d2wmba1 (2wmb A:1-296)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (374 PDB entries)
   Uniprot P24941

8. Domain d2wmba1: 2wmb A:1-296 [169445]
   Other proteins in same PDB: d2wmba2, d2wmbc2
   automated match to d1vywa_
   complexed with mg

Details for d2wmba1

PDB Entry: 2wmb, 2.6 Å

PDB Description: structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin a

PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2wmba1:

Sequence; same for both SEQRES and ATOM records:

>d2wmba1 d.144.1.7 (A:1-296) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d2wmba1:

• d2wmba1 first appeared in SCOPe 2.01, called d2wmba_
  
• d2wmba1 was called d2wmba_ in SCOPe 2.05
  
• d2wmba1 appears in SCOPe 2.07
  
• d2wmba1 appears in the current release, SCOPe 2.08