SCOPe 2.06: Domain d2vh6a_: 2vh6 A:

Lineage for d2vh6a_ (2vh6 A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein automated matches [190044] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (146 PDB entries)

8. Domain d2vh6a_: 2vh6 A: [168600]
   Other proteins in same PDB: d2vh6b_
   automated match to d1c5md_
   complexed with gsv

Details for d2vh6a_

PDB Entry: 2vh6, 1.95 Å

PDB Description: structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with biaryl p4 motifs

PDB Compounds: (A:) activated factor xa heavy chain

SCOPe Domain Sequences for d2vh6a_:

Sequence, based on SEQRES records:

>d2vh6a_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Sequence, based on observed residues (ATOM records):

>d2vh6a_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qegeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtq
ktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacq
gdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d2vh6a_:

• d2vh6a_ first appeared in SCOPe 2.01
  
• d2vh6a_ appears in SCOPe 2.05
  
• d2vh6a_ appears in SCOPe 2.07
  
• d2vh6a_ appears in the current release, SCOPe 2.08