SCOPe 2.08: Domain d2vh0a_: 2vh0 A:

Lineage for d2vh0a_ (2vh0 A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein automated matches [190044] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (141 PDB entries)

8. Domain d2vh0a_: 2vh0 A: [168599]
   Other proteins in same PDB: d2vh0b_
   automated match to d1c5md_
   complexed with ca, gsi, mg

Details for d2vh0a_

PDB Entry: 2vh0, 1.7 Å

PDB Description: structure and property based design of factor xa inhibitors:biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs

PDB Compounds: (A:) activated factor xa heavy chain

SCOPe Domain Sequences for d2vh0a_:

Sequence; same for both SEQRES and ATOM records:

>d2vh0a_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d2vh0a_:

• d2vh0a_ first appeared in SCOPe 2.01
  
• d2vh0a_ appears in SCOPe 2.07