Lineage for d2vgia2 (2vgi A:57-159,A:262-439)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1336838Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 1344393Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families) (S)
  5. 1344394Family c.1.12.1: Pyruvate kinase [51622] (1 protein)
  6. 1344395Protein Pyruvate kinase, N-terminal domain [51623] (6 species)
    this domain is interrupted by an all-beta domain
    C-terminal domain is alpha/beta
  7. 1344416Species Human (Homo sapiens) [TaxId:9606] [82273] (4 PDB entries)
  8. 1344429Domain d2vgia2: 2vgi A:57-159,A:262-439 [168577]
    Other proteins in same PDB: d2vgia1, d2vgia3, d2vgib1, d2vgib3, d2vgic1, d2vgic3, d2vgid1, d2vgid3
    complexed with fbp, k, mn, pga; mutant

Details for d2vgia2

PDB Entry: 2vgi (more details), 2.87 Å

PDB Description: human erythrocyte pyruvate kinase: r486w mutant
PDB Compounds: (A:) pyruvate kinase isozymes r/l

SCOPe Domain Sequences for d2vgia2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2vgia2 c.1.12.1 (A:57-159,A:262-439) Pyruvate kinase, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2vgia2:

Click to download the PDB-style file with coordinates for d2vgia2.
(The format of our PDB-style files is described here.)

Timeline for d2vgia2: