Lineage for d1iara_ (1iar A:)

  1. Root: SCOP 1.65
  2. 275720Class a: All alpha proteins [46456] (179 folds)
  3. 280090Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 280091Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglments of the two crossover connections
  5. 280157Family a.26.1.2: Short-chain cytokines [47286] (10 proteins)
  6. 280198Protein Interleukin-4 (IL-4) [47291] (1 species)
  7. 280199Species Human (Homo sapiens) [TaxId:9606] [47292] (13 PDB entries)
  8. 280201Domain d1iara_: 1iar A: [16853]
    Other proteins in same PDB: d1iarb1, d1iarb2
    mutant

Details for d1iara_

PDB Entry: 1iar (more details), 2.3 Å

PDB Description: interleukin-4 / receptor alpha chain complex

SCOP Domain Sequences for d1iara_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1iara_ a.26.1.2 (A:) Interleukin-4 (IL-4) {Human (Homo sapiens)}
hkcditlqeiiktlnslteqktlcteltvtdifaaskntteketfcraatvlrqfyshhe
kdtrclgataqqfhrhkqlirflkrldrnlwglaglnscpvkeanqstlenflerlktim
rekyskcss

SCOP Domain Coordinates for d1iara_:

Click to download the PDB-style file with coordinates for d1iara_.
(The format of our PDB-style files is described here.)

Timeline for d1iara_: