SCOPe 2.08: Domain d2qb2a_: 2qb2 A:

Lineage for d2qb2a_ (2qb2 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families)

5. Family c.67.1.1: AAT-like [53384] (17 proteins)

6. Protein Aspartate aminotransferase, AAT [53385] (9 species)

7. Species Escherichia coli [TaxId:562] [53390] (84 PDB entries)
   Uniprot P00509

8. Domain d2qb2a_: 2qb2 A: [167505]
   automated match to d1aama_
   complexed with gol, pmp, psz, so4

Details for d2qb2a_

PDB Entry: 2qb2, 1.7 Å

PDB Description: Structural Studies Reveal the Inactivation of E. coli L-aspartate aminotransferase by (s)-4,5-dihydro-2thiophenecarboylic acid (SADTA) via two mechanisms (at pH 7.0).

PDB Compounds: (A:) aspartate aminotransferase

SCOPe Domain Sequences for d2qb2a_:

Sequence, based on SEQRES records:

>d2qb2a_ c.67.1.1 (A:) Aspartate aminotransferase, AAT {Escherichia coli [TaxId: 562]}
mfenitaapadpilgladlfraderpgkinlgigvykdetgktpvltsvkkaeqyllene
ttknylgidgipefgrctqellfgkgsalindkrartaqtpggtgalrvaadflakntsv
krvwvsnpswpnhksvfnsaglevreyayydaenhtldfdalinslneaqagdvvlfhgc
chnptgidptleqwqtlaqlsvekgwlplfdfayqgfargleedaeglrafaamhkeliv
assysknfglynervgactlvaadsetvdrafsqmkaairanysnppahgasvvatilsn
dalraiweqeltdmrqriqrmrqlfvntlqekganrdfsfiikqngmfsfsgltkeqvlr
lreefgvyavasgrvnvagmtpdnmaplceaivavl

Sequence, based on observed residues (ATOM records):

>d2qb2a_ c.67.1.1 (A:) Aspartate aminotransferase, AAT {Escherichia coli [TaxId: 562]}
mfenitaapdlfradkinlgigvykdetgktpvltsvkkaeqyllenettknylgidgip
efgrctqellfgkgsalindkrartaqtpggtgalrvaadflakntsvkrvwvsnpswpn
hksvfnsaglevreyayydaenhtldfdalinslneaqagdvvlfhgcchnptgidptle
qwqtlaqlsvekgwlplfdfayqgfargleedaeglrafaamhkelivassysknfglyn
ervgactlvaadsetvdrafsqmkaairanysnppahgasvvatilsndalraiweqelt
dmrqriqrmrqlfvntlqekganrdfsfiikqngmfsfsgltkeqvlrlreefgvyavas
grvnvagmtpdnmaplceaivavl

Timeline for d2qb2a_:

• d2qb2a_ first appeared in SCOPe 2.01
  
• d2qb2a_ appears in SCOPe 2.07