SCOPe 2.06: Domain d2o6xa_: 2o6x A:

Lineage for d2o6xa_ (2o6x A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.0: automated matches [191342] (1 protein)
   not a true family

6. Protein automated matches [190230] (20 species)
   not a true protein

7. Species Fasciola hepatica [TaxId:6192] [188299] (1 PDB entry)

8. Domain d2o6xa_: 2o6x A: [166568]
   automated match to d1by8a_

Details for d2o6xa_

PDB Entry: 2o6x, 1.4 Å

PDB Description: crystal structure of procathepsin l1 from fasciola hepatica

PDB Compounds: (A:) Secreted cathepsin L 1

SCOPe Domain Sequences for d2o6xa_:

Sequence, based on SEQRES records:

>d2o6xa_ d.3.1.0 (A:) automated matches {Fasciola hepatica [TaxId: 6192]}
nddlwhqwkrmynkeyngaddqhrrniweknvkhiqehnlrhdlglvtytlglnqftdmt
feefkakyltemsrasdilshgvpyeannravpdkidwresgyvtevkdqgncgsgwafs
ttgtmegqymknertsisfseqqlvdcsrpwgnngcggglmenayqylkqfgletessyp
ytavegqcrynkqlgvakvtgfytvhsgsevelknlvgaegpaavavdvesdfmmyrsgi
yqsqtcsplrvnhavlavgygtqggtdywivknswglswgergyirmvrnrgnmcgiasl
aslpmvarfp

Sequence, based on observed residues (ATOM records):

>d2o6xa_ d.3.1.0 (A:) automated matches {Fasciola hepatica [TaxId: 6192]}
nddlwhqwkrmynkeyngaddqhrrniweknvkhiqehnlrhdlglvtytlglnqftdmt
feefkakyltemsrasdilshgvpyeavpdkidwresgyvtevkdqgncgsgwafsttgt
megqymknertsisfseqqlvdcsrpwgnngcggglmenayqylkqfgletessypytav
egqcrynkqlgvakvtgfytvhsgsevelknlvgaegpaavavdvesdfmmyrsgiyqsq
tcsplrvnhavlavgygtqggtdywivknswglswgergyirmvrnrgnmcgiaslaslp
mvarfp

Timeline for d2o6xa_:

• d2o6xa_ first appeared in SCOPe 2.01
  
• d2o6xa_ appears in SCOPe 2.05
  
• d2o6xa_ appears in SCOPe 2.07
  
• d2o6xa_ appears in the current release, SCOPe 2.08