SCOPe 2.08: Domain d2o3ea_: 2o3e A:

Lineage for d2o3ea_ (2o3e A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
   combines M2, M3 and M32 families of metalloproteases
   the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

6. Protein automated matches [190340] (5 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [187944] (2 PDB entries)

8. Domain d2o3ea_: 2o3e A: [166519]
   automated match to d1i1ip_
   complexed with zn

Details for d2o3ea_

PDB Entry: 2o3e, 2.2 Å

PDB Description: crystal structure of engineered neurolysin with thimet oligopeptidase specificity for neurotensin cleavage site.

PDB Compounds: (A:) Neurolysin

SCOPe Domain Sequences for d2o3ea_:

Sequence; same for both SEQRES and ATOM records:

>d2o3ea_ d.92.1.5 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
mssytaagrnvlrwdlspeqiktrteqliaqtkqvydtvgtialkevtyenclqvladie
vtyivertmldfpqhvssdrevraasteadkklsrfdiemsmredvfqrivhlqetcdle
kikpearryleksikmgkrnglhlsehirneiksmkkrmselcidfnknlneddtslvfs
kaelgalpddfidslektdedkykvtlkyphyfpvmkkccvpetrrkmemafhtrckqen
tailqqllplraqvakllgynthadfvlelntakstsrvaaflddlsqklkplgeaeref
ilslkkkeceergfeydgkinawdlhyymtqteelkysvdqeslkeyfpievvtegllsi
yqellglsfeqvpdahvwnksvslytvkdkatgevlgqfyldlypregkynhaacfglqp
gcllpdgsrmmsvaalvvnfsqpvagrpsllrhdevetyfhefghvmhqicaqtdfarfs
gtnverdfvevpsqmlenwvwdvdslrklskhykdghpitdelleklvasrlvntglltl
rqivlskvdqslhtnatldaaseyakycteilgvaatpgtnmpatfghlaggydgqyygy
lwsevfsmdmfhscfkkegimnpevgmkyrnlilkpggsldgmdmlqnflqrepnqkafl
msrgl

Timeline for d2o3ea_:

• d2o3ea_ first appeared in SCOPe 2.01
  
• d2o3ea_ appears in SCOPe 2.07