SCOPe 2.02: Domain d2isha_: 2ish A:

Lineage for d2isha_ (2ish A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein automated matches [190410] (1 species)
   not a true protein

7. Species Clostridium botulinum [TaxId:1491] [187385] (12 PDB entries)

8. Domain d2isha_: 2ish A: [165674]
   automated match to d1xtfa_
   complexed with zn

Details for d2isha_

PDB Entry: 2ish, 2 Å

PDB Description: Botulinum Neurotoxin A Light Chain WT Crystal Form C

PDB Compounds: (A:) Neurotoxin BoNT/A

SCOPe Domain Sequences for d2isha_:

Sequence; same for both SEQRES and ATOM records:

>d2isha_ d.92.1.7 (A:) automated matches {Clostridium botulinum [TaxId: 1491]}
pfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnp
ppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggs
tidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngyg
stqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpnr
vfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkak
sivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvl
nrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklk

Timeline for d2isha_:

• d2isha_ first appeared in SCOPe 2.01
  
• d2isha_ appears in SCOPe 2.03
  
• d2isha_ appears in the current release, SCOPe 2.08