SCOPe 2.07: Domain d2isea1: 2ise A:2-420

Lineage for d2isea1 (2ise A:2-420)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein automated matches [190410] (2 species)
   not a true protein

7. Species Clostridium botulinum [TaxId:1491] [187385] (26 PDB entries)

8. Domain d2isea1: 2ise A:2-420 [165670]
   Other proteins in same PDB: d2isea2, d2iseb2
   automated match to d1xtfa_
   complexed with zn

Details for d2isea1

PDB Entry: 2ise, 2.2 Å

PDB Description: Botulinum Neurotoxin A Light Chain WT Crystal Form A

PDB Compounds: (A:) Neurotoxin BoNT/A

SCOPe Domain Sequences for d2isea1:

Sequence; same for both SEQRES and ATOM records:

>d2isea1 d.92.1.7 (A:2-420) automated matches {Clostridium botulinum [TaxId: 1491]}
pfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnp
ppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggs
tidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngyg
stqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpnr
vfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkak
sivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvl
nrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklknft

Timeline for d2isea1:

• d2isea1 first appeared in SCOPe 2.01, called d2isea_
  
• d2isea1 appears in SCOPe 2.06
  
• d2isea1 appears in the current release, SCOPe 2.08