SCOP 1.63: Domain d1or2a_: 1or2 A:

Lineage for d1or2a_ (1or2 A:)

1. Root: SCOP 1.63

2. Class a: All alpha proteins [46456] (171 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (16 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.1: Apolipoprotein [47162] (1 family)

5. Family a.24.1.1: Apolipoprotein [47163] (3 proteins)
   Can exist in a coiled-coil oligomeric form, see PDB entry 1AV1
   family may also include the five-helical bundle protein Apolipophorin-III

6. Protein Apolipoprotein E3 [47164] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47165] (7 PDB entries)

8. Domain d1or2a_: 1or2 A: [16525]
   truncation mutant 165

Details for d1or2a_

PDB Entry: 1or2, 2.5 Å

PDB Description: apolipoprotein e3 (apoe3) truncation mutant 165

SCOP Domain Sequences for d1or2a_:

Sequence, based on SEQRES records:

>d1or2a_ a.24.1.1 (A:) Apolipoprotein E3 {Human (Homo sapiens)}
gqrwelalgrfwdylrwvqtlseqvqeellssqvtqelralmdetmkelkaykseleeql
tpvaeetrarlskelqaaqarlgadmedvcgrlvqyrgevqamlgqsteelrvrlashlr
klrkrllrdaddlqkrlavyq

Sequence, based on observed residues (ATOM records):

>d1or2a_ a.24.1.1 (A:) Apolipoprotein E3 {Human (Homo sapiens)}
gqrwelalgrfwdylrwvqtlseqvqeellssqvtqelralmdetmkelkaykseleeql
skelqaaqarlgadmedvcgrlvqyrgevqamlgqsteelrvrlashlrklrkrllrdad
dlqkrlavyq

Timeline for d1or2a_:

• d1or2a_ first appeared (with stable ids) in SCOP 1.55
  
• d1or2a_ appears in SCOP 1.61
  
• d1or2a_ appears in SCOP 1.65
  
• d1or2a_ appears in the current release, SCOPe 2.08