SCOPe 2.01: Domain d2hela_: 2hel A:

Lineage for d2hela_ (2hel A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [187169] (25 PDB entries)

8. Domain d2hela_: 2hel A: [165074]
   automated match to d1jpaa_
   mutant

Details for d2hela_

PDB Entry: 2hel, 2.35 Å

PDB Description: crystal structure of a mutant epha4 kinase domain (y742a)

PDB Compounds: (A:) Eph receptor A4

SCOPe Domain Sequences for d2hela_:

Sequence, based on SEQRES records:

>d2hela_ d.144.1.7 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
akeidascikiekvigvgefgevcsgrlkvpgkreicvaiktlkagytdkqrrdflseas
imgqfdhpniihlegvvtkckpvmiiteymengsldaflrkndgrftviqlvgmlrgigs
gmkylsdmsavhrdlaarnilvnsnlvckvsdfgmsrvleddpeaayttrggkipirwta
peaiayrkftsasdvwsygivmwevmsygerpywdmsnqdvikaieegyrlpppmdcpia
lhqlmldcwqkersdrpkfgqivnmldklirnpnsl

Sequence, based on observed residues (ATOM records):

>d2hela_ d.144.1.7 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
akeidascikiekvigvgefgevcsgrlkveicvaiktlkytdkqrrdflseasimgqfd
hpniihlegvvtkckpvmiiteymengsldaflrkndgrftviqlvgmlrgigsgmkyls
dmsavhrdlaarnilvnsnlvckvsdfgmsrvkipirwtapeaiayrkftsasdvwsygi
vmwevmsygerpywdmsnqdvikaieegyrlpppmdcpialhqlmldcwqkersdrpkfg
qivnmldklirnpnsl

Timeline for d2hela_:

• d2hela_ is new in SCOPe 2.01-stable
  
• d2hela_ appears in SCOPe 2.02
  
• d2hela_ appears in the current release, SCOPe 2.08