SCOPe 2.08: Domain d2gp0a_: 2gp0 A:

Lineage for d2gp0a_ (2gp0 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d2gp0a_: 2gp0 A: [164789]
   automated match to d1jlna_
   complexed with gol, po4; mutant

Details for d2gp0a_

PDB Entry: 2gp0, 2.05 Å

PDB Description: heptp catalytic domain (residues 44-339), s225d mutant

PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 7

SCOPe Domain Sequences for d2gp0a_:

Sequence, based on SEQRES records:

>d2gp0a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvspedldipghaskdr
yktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpmpntvsdfwemvw
qeevslivmltqlregkekcvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeer
rdvkhilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhcsagigrtgcfiat
rigcqqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalyagqlpe

Sequence, based on observed residues (ATOM records):

>d2gp0a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvspedldipghaskdr
yktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpmpntvsdfwemvw
qeevslivmltqlrecvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeerrdvk
hilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhcsagigrtgcfiatrigc
qqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalyagqlpe

Timeline for d2gp0a_:

• d2gp0a_ first appeared in SCOPe 2.01
  
• d2gp0a_ appears in SCOPe 2.07