Lineage for d2fhhf_ (2fhh F:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1222614Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 1222615Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 1222781Family d.153.1.4: Proteasome subunits [56251] (4 proteins)
  6. 1223777Protein automated matches [190144] (8 species)
    not a true protein
  7. 1223908Species Mycobacterium tuberculosis [TaxId:1773] [187707] (9 PDB entries)
  8. 1224098Domain d2fhhf_: 2fhh F: [164368]
    automated match to d1q5qa_
    complexed with m1n

Details for d2fhhf_

PDB Entry: 2fhh (more details), 2.99 Å

PDB Description: Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with a peptidyl boronate inhibitor MLN-273
PDB Compounds: (F:) 20S proteasome, alpha and beta subunits

SCOPe Domain Sequences for d2fhhf_:

Sequence, based on SEQRES records: (download)

>d2fhhf_ d.153.1.4 (F:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
speqamrerselarkgiaraksvvalayaggvlfvaenpsrslqkiselydrvgfaaagk
fnefdnlrrggiqfadtrgyaydrrdvtgrqlanvyaqtlgtifteqakpyevelcvaev
ahygetkrpelyritydgsiadephfvvmggttepianalkesyaenasltdalriavaa
lragsadtsggdqptlgvaslevavldanrprrafrritgsalqallvdq

Sequence, based on observed residues (ATOM records): (download)

>d2fhhf_ d.153.1.4 (F:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
speqamrerselarkgiaraksvvalayaggvlfvaenpsrslqkiselydrvgfaaagk
fnefdnlrrggiqfadtrgyaydrrdvtgrqlanvyaqtlgtifteqakpyevelcvaev
ahygetkrpelyritydgsiadephfvvmggttepianalkesyaenasltdalriavaa
lragslgvaslevavldanrprrafrritgsalqallvdq

SCOPe Domain Coordinates for d2fhhf_:

Click to download the PDB-style file with coordinates for d2fhhf_.
(The format of our PDB-style files is described here.)

Timeline for d2fhhf_: