SCOPe 2.02: Domain d2b1za_: 2b1z A:

Lineage for d2b1za_ (2b1z A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (58 PDB entries)
   Uniprot P03372 307-551

8. Domain d2b1za_: 2b1z A: [162969]
   automated match to d1qkua_
   complexed with 17m

Details for d2b1za_

PDB Entry: 2b1z, 1.78 Å

PDB Description: human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 nr box ii peptide

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d2b1za_:

Sequence, based on SEQRES records:

>d2b1za_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllleml
dahr

Sequence, based on observed residues (ATOM records):

>d2b1za_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytfekdhihrvldkitdtlihlmaka
gltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahr

Timeline for d2b1za_:

• d2b1za_ first appeared in SCOPe 2.01
  
• d2b1za_ appears in SCOPe 2.03
  
• d2b1za_ appears in the current release, SCOPe 2.08