SCOPe 2.08: Domain d2ax0a_: 2ax0 A:

Lineage for d2ax0a_ (2ax0 A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus [TaxId:11103] [187048] (44 PDB entries)

8. Domain d2ax0a_: 2ax0 A: [162939]
   automated match to d1nb4a_
   protein/RNA complex; complexed with 5x, so4

Details for d2ax0a_

PDB Entry: 2ax0, 2 Å

PDB Description: hepatitis c virus ns5b rna polymerase in complex with a covalent inhibitor (5x)

PDB Compounds: (A:) Genome polyprotein

SCOPe Domain Sequences for d2ax0a_:

Sequence, based on SEQRES records:

>d2ax0a_ e.8.1.4 (A:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrawrhrarnvrarllsrggraaicgkylfnwavktklkltpia
aagrldlsswftagysggdiyh

Sequence, based on observed residues (ATOM records):

>d2ax0a_ e.8.1.4 (A:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrawrhrarnvrarllsrggraaicgkylfnwavktklkltpia
swftagysggdiyh

Timeline for d2ax0a_:

• d2ax0a_ first appeared in SCOPe 2.01
  
• d2ax0a_ appears in SCOPe 2.07