SCOPe 2.01: Domain d1yhva_: 1yhv A:

Lineage for d1yhva_ (1yhv A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein pak1 [56146] (1 species)
   OPK group; PAK/STE20 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56147] (9 PDB entries)

8. Domain d1yhva_: 1yhv A: [162206]
   automated match to d1f3mc_
   mutant

Details for d1yhva_

PDB Entry: 1yhv, 1.8 Å

PDB Description: crystal structure of pak1 kinase domain with two point mutations (k299r, t423e)

PDB Compounds: (A:) Serine/threonine-protein kinase PAK 1

SCOPe Domain Sequences for d1yhva_:

Sequence; same for both SEQRES and ATOM records:

>d1yhva_ d.144.1.7 (A:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpeqskrsemvgtp
ywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpe
klsaifrdflnrcldmdvekrgsakellqhqflkiakplssltpliaaakeat

Timeline for d1yhva_:

• d1yhva_ is new in SCOPe 2.01-stable
  
• d1yhva_ appears in SCOPe 2.02
  
• d1yhva_ appears in the current release, SCOPe 2.08