SCOPe 2.03: Domain d1wzya_: 1wzy A:

Lineage for d1wzya_ (1wzy A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d1wzya_: 1wzy A: [162012]
   automated match to d1erka_
   complexed with f29

Details for d1wzya_

PDB Entry: 1wzy, 2.5 Å

PDB Description: crystal structure of human erk2 complexed with a pyrazolopyridazine derivative

PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d1wzya_:

Sequence; same for both SEQRES and ATOM records:

>d1wzya_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgfltey
vatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsp
sqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqa
lahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpg

Timeline for d1wzya_:

• d1wzya_ first appeared in SCOPe 2.01
  
• d1wzya_ appears in SCOPe 2.02
  
• d1wzya_ appears in SCOPe 2.04
  
• d1wzya_ appears in the current release, SCOPe 2.08