SCOPe 2.03: Domain d3e0wa2: 3e0w A:7-87,A:187-357

Lineage for d3e0wa2 (3e0w A:7-87,A:187-357)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families)

5. Family c.1.12.1: Pyruvate kinase [51622] (1 protein)

6. Protein Pyruvate kinase, N-terminal domain [51623] (6 species)
   this domain is interrupted by an all-beta domain
   C-terminal domain is alpha/beta

7. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [51626] (11 PDB entries)

8. Domain d3e0wa2: 3e0w A:7-87,A:187-357 [157967]
   Other proteins in same PDB: d3e0wa1, d3e0wa3
   automatically matched to d1pkla2

Details for d3e0wa2

PDB Entry: 3e0w, 3.1 Å

PDB Description: crystal structure of pyruvate kinase from leishmania mexicana

PDB Compounds: (A:) pyruvate kinase

SCOPe Domain Sequences for d3e0wa2:

Sequence; same for both SEQRES and ATOM records:

>d3e0wa2 c.1.12.1 (A:7-87,A:187-357) Pyruvate kinase, N-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
ltlsifdpvanyraariictigpstqsvealkgliqsgmsvarmnfshgsheyhqttinn
vrqaaaelgvniaialdtkgpXpavsakdrvdlqfgveqgvdmifasfirsaeqvgdvrk
algpkgrdimiickienhqgvqnidsiieesdgimvargdlgveipaekvvvaqkilisk
cnvagkpvicatqmlesmtynprptraevsdvanavfngadcvmlsgetakgkypnevvq
ymaricleaqsal

Timeline for d3e0wa2:

• d3e0wa2 first appeared in SCOP 1.75
  
• d3e0wa2 appears in SCOPe 2.02
  
• d3e0wa2 appears in SCOPe 2.04
  
• d3e0wa2 appears in the current release, SCOPe 2.08